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Archive for the ‘conflicts of interest’ Category

Aluminum adjuvants, autoimmune diseases, and attempted suppression of the truth

Posted by Henry Bauer on 2019/03/24

An earlier post (Adjuvants — the poisons hidden in some vaccines) described the danger that aluminum adjuvants in vaccines pose, including that they may indeed be associated with a risk of inducing autism. A recent book, How to End the Autism Epidemic,   underscores that risk and exposes what should be the crippling, disqualifying conflicts of interest of one of the most prominent accepted experts on vaccinations. I had learned about this from a splendidly informative article by Celeste McGovern at Ghost Ship Media (Prescription to end the autism epidemic, 17 September 2018).

It turns out that animals as well as human beings have experienced tangible harm from vaccines containing aluminum adjuvants: in particular, sheep. Celeste McGovern has reported about that in other recent posts:
Spanish sheep study finds vaccine aluminum in lymph nodes more than a year after injection, behavioural changes, 3 November 2018; Vaccines induce bizarre anti-social behaviour in sheep, 6 November 2018; Anatomy of a science study censorship, 20 March 2019.

This last piece describes the attempt to prevent the truth about aluminum adjuvants from becoming public knowledge, by pressuring the publisher, Elsevier, to withdraw an already accepted, peer-reviewed article in one of its journals: “Cognition and behavior in sheep repetitively inoculated with aluminum adjuvant-containing vaccines or aluminum adjuvant only”, by Javier Asína et al., published online in Pharmacological Research before being withdrawn. Fortunately there are   nowadays resources on the Internet that make it more difficult for the censors to do their dirty work. One invaluable resource is the Wayback Machine, which too few people seem to know about. In the present case, a PDF of the Asína et al. article, as accepted and published online as “In Press” in Pharmacological Research, is available at ResearchGate.

Elsevier publishes thousands of scientific and medical journals, including in the past some that were actually advertisements written by and paid for by pharmaceutical companies, presented dishonestly and misleadingly as genuine scientific periodicals: Elsevier published 6 fake journals); Elsevier had a whole division publishing fake medical journals).

Elsevier had also engaged in censorship on earlier occasions, in one case to the extent of emasculating a well respected, independent publication, Medical Hypotheses (see Chapter 3, “A Public Act of Censorship: Elsevier and Medical Hypotheses”, in Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth).

If the shenanigans and cover-ups about aluminum adjuvants make an insufficiently alarming horror story,   please look at yet another article by Celeste McGovern: Poisoned in Slow Motion, 1 October 2018:

“Immune-system disease is sweeping the globe. . . . Autoimmune/inflammatory syndrome induced by adjuvants, or ASIA — a wildly unpredictable inflammatory response to foreign substances injected or inserted into the human body . . . . The medical literature contains hundreds of such cases. . . . [with] vague and sundry symptoms — chronic fatigue, muscle and joint pain, sleep disturbances, cognitive impairment, skin rashes and more . . . that . . . share the common underlying trigger of certain immune signaling pathways. Sometimes this low-grade inflammation can smolder for years only to suddenly incite an overt autoimmune disease. . . . Chronic fatigue syndrome (also known as myalgic encephalitis), once a rare “hypochondriac” disorder, now affects millions of people globally and has been strongly associated with markers of immune system dysfunction. . . . One in thirteen American children has a hyperactive immune system resulting in food allergy,4 and asthma, another chronic inflammatory disease of the immune system, affects 300 million people across the globe.5 Severe neurological disorders like autism (which now affects one in 22 boys in some US states) have soared from virtual nonexistence and are also linked to a damaged immune system.”

[4. Pediatrics, 2011; 128: e9-17
5. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. 2008.
6. Eur J Pediatr, 2014; 173: 33-43]

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These particulars offer further illustrations of the general points that I have been making for some time:

 Science and medicine have become dogmatic wielders of authority through being co-opted and in effect bought out by commercial interests. Pharmaceutical companies are perhaps in the forefront of this takeover, but the influence of other industries should not be forgotten, for instance that of Monsanto with its interest in Genetically Modified products; see Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth, Jefferson (NC): McFarland 2012

 Science, research, medicine, are very different things nowadays than they were up to about the middle of the 20th century, and very different from the conventional wisdom about them. Media, policy makers, and the public need an independent, impartial assessment of what science and medicine are said to have established; needed is  a Science Court; see Science Is Not What You Think: How It Has Changed, Why We Can’t Trust It, How It Can Be Fixed, McFarland, 2017

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Posted in conflicts of interest, fraud in medicine, fraud in science, legal considerations, media flaws, medical practices, peer review, prescription drugs, science is not truth, scientific culture, scientific literacy, scientism, scientists are human, unwarranted dogmatism in science | Tagged: , , , , , , | Leave a Comment »

Optimal peer review for guiding public policy: A Science Court

Posted by Henry Bauer on 2019/01/29

“Peer review” is widely regarded as the mechanism by which science manages to produce impartial, unbiased, objective facts and interpretations. As with so many popular notions about scientific activity, this is very far from the truth [1].

Innumerable observers and practicing researchers have written copiously about the many things that are wrong with peer review [2]. Contemporary practices of peer review are only about a century old. They began simply as a way of assisting editors of journals to assess the merits for publication of manuscripts too specialized for the editorial staff itself it to render judgment. The need for such specialized advice was not unrelated to the enormous expansion of scientific activity that followed World War II, bringing an ever-increasing demand for space in scientific periodicals as well as ever-increasing competition between researchers for funding and for getting published as a necessary prerequisite for career advancement and resources for research.

At any rate, peer review in science is no more impartial, unbiased, or objective than is criticism of art, music, film, or literary products. One illustration of that: it is becoming quite common for journal editors to ask the authors of submitted manuscripts whether there are individuals who should not be asked to serve as peer reviewers because of their known biases or hostility against the authors. Another point: Peer reviewers are typically chosen because they work on much the same topic as that of the manuscript to be reviewed; thereby they are likely to be to some extent competitors or allies, conflicts of interest that ought to be disbarring.

Modern (post-16th-17th-century) science managed to progress and to succeed quite magnificently for several centuries without the current practices of systematic peer-review. The assessing of already published work through further research and commentary gave science the appearance and the effect of being eventually self-correcting. Note “eventually”: the trials and errors and that preceded correction, sometimes for very long periods indeed, were of concern only within the specialized scientific communities, they were not any problem for the wider society.

Nowadays, however, society in general and industries and governments in particular have come to look to contemporary science for immediate guidance to significant actions and policies. That makes the fact that peer review is not impartial or objective quite important, and indeed dangerous. The nature of scientific activity and of the scientific community is such that the consensus among those who happen to be the most prominent researchers in any given field comes to control what research gets funded, which results get published and which are suppressed, and what the media and the public and policy-makers take to be “what science says”.

Unfortunately, the history of science is far from widely known or appreciated, most notably the fact that the contemporary scientific consensus at any given time has almost invariably turned out, sooner or later, to have been flawed, in minor or major ways.

Ignorance of the history of science, together with the misguided view that any prominent contemporary scientific consensus can be safely relied upon to guide social and political actions on any matters that are technical, including matters of medicine and public health, have already resulted in widespread actions that have brought tangible harm on such issues as supposedly human-caused global warming and climate change [3] and the mistaken belief is that AIDS was caused by a novel virus that destroys the immune system [4]. The closest precedent for these contemporary mistakes seems to be the ideology of eugenics, which led to the forced sterilization of tens of thousands of Americans over a period of more than half a century.

Since peer-review is not effectively making science contemporaneously objective and reliable, on matters of social and political importance policymakers badly need some other way to counteract the bias and dogmatic single-mindedness of any contemporary scientific consensus. The only conceivable mechanism to that end would seem to be something like an Institution of Scientific Judgment, as Arthur Kantrowitz suggested half a century ago [5], a concept that has come to be described as a Science Court [6].

 

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[1]  Science Is Not What You Think — how it has changed, why we can’t trust it, how it can be fixed (McFarland, 2017)

[2]  pp. 106-9 in [1] and sources cited there

[3]  “What everyone ought to know about global warming and climate change: an unbiased review”referring to “#16 A Summary” by Don Aitkin

[4]  The Case against HIV  and sources cited there

[5]  Arthur Kantrowitz, “Proposal for an Institution for Scientific Judgment”, Science, 156 (1967) 763–4.

[6]  Chapter 12 in [1] and sources cited there

Posted in conflicts of interest, consensus, funding research, global warming, media flaws, peer review, politics and science, science is not truth, science policy, scientific culture, scientists are human, unwarranted dogmatism in science | Tagged: , | Leave a Comment »

The Case for a Science Court

Posted by Henry Bauer on 2019/01/24

I mentioned the concept of a Science Court in a previous post on this blog: “Who guards the guardians? Who guards science?”

and I’ve mentioned it in a number of other places as well. Sometimes those mentions have brought comments on a variety of blogs. Some raised objections to the idea, unfortunately most commonly individuals who have not read my full discussion of the concept, which comprises the 20 pages of chapter 12 in my latest book, “Science Is Not What You Think”  (see reviews of it).

Obviously I cannot reproduce here the 20 pages of that book chapter. Here are the salient points:

Ø     Nowadays, science is almost universally taken as the ultimate authority on knowledge about the natural world

Ø     Media, pundits, policymakers, and governments accept as reliable knowledge what science says

Ø     “What science says” is taken to be the contemporary “scientific consensus”, the mainstream view, the view held by the contemporary elite group of experts on the given topic

Ø     The history of science is unequivocal, that any given contemporary scientific consensus has been quite often significantly mistaken

Ø     History also records that contemporary experts who dissented from the scientific consensus sometimes — though by no means always — turn out to have been closer to the truth and then the consensus was

Ø     Society at large, and policymakers in particular, would benefit from an impartial independent assessment of the evidence respectively for and against the contemporary consensus. The aim of a Science Court would be precisely to facilitate such an impartial independent assessment.

The need for such an institution is nowadays quite pressing because on a whole host of topics there is no substantive, open, public, debate between proponents and challengers of the contemporary consensus. Many of those topics are of little or no immediate practical public significance, say, what the mechanism is of the sense of smell, or what caused the extinction of dinosaurs, or some other matters discussed in my earlier book, Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth (2012) .

However, there are also some topics of prime human, social, political importance on which informed and qualified experts have offered strong evidence that the contemporary consensus is dangerously flawed: HIV/AIDS, human-caused global warming and climate change, the role of prescription drugs in preventive medicine. On those, the popular media illustrate well enough that official institutions accept the scientific consensus and dismiss all challenges as “denialism”, no matter how eminent are the challengers. Something like a Science Court would seem to be the only conceivable mechanism by which the consensus could be forced to confront openly and substantively the challenges to its hegemonic, dogmatically held, view.

In my chapter-length discussion, I consider also the following:

Ø     The formal structure, sponsorship, authority and powers of the Science Court

Ø     Staffing of the Court: permanent and also ad hoc as appropriate to each specific topic

Ø     The choice of advocates for and against, on each particular topic

Ø     The choice of which issues are to be considered by the Court

My chapter discusses the benefits the Science Court would bring on questions concerning prescription drugs, climate change, and HIV/AIDS. It also describes the history of the concept of a Science Court, which dates back half a century to qualms about the potential safety of generating power in nuclear reactors, when equally qualified experts were arguing both sides of the issue. In more recent times, several legal scholars have argued that a specifically Science Court would be of considerable benefit to the judicial system in general and as a whole, since that system is called on increasingly to decide cases in which central questions involve scientific evidence and the qualifications of expert witnesses.

The pressing need for a Science Court nowadays arises because the scientific consensus cannot be relied upon to deliver the benefits that “science” supposedly brings, namely, the best available impartial, objective, unbiased assessment of what is actually known, what “science” has established.

Science did indeed bring those benefits for the first several centuries of what is generally called “modern science”, beginning around the 16th/17th centuries or so with the Reformation and the subsequent Enlightenment. What has not yet been widely enough recognized is how different scientific activity is since the middle of the 20th century, by comparison with those earlier centuries of modern science. Those differences are described in considerable detail in chapter 1 of my recent book; in a nutshell:

The circumstances of scientific activity have changed, from about pre-WWII to nowadays, from a cottage industry of voluntarily cooperating, independent, largely disinterested ivory-tower intellectual entrepreneurs, where science was free to do its own thing, namely the unfettered seeking of truth about the natural world; to nowadays a bureaucratic corporate-industry-government behemoth in which science has been pervasively co-opted by outside interests and is not free to do its own thing because of the omnipresent conflicts of interest. Influences and interests outside science now control the choices of research projects and the decisions of what to publish and what not to make public.

Aspects of that change were noted by John Burnham in his book, How Superstition Won and Science Lost (1987), and by Jacques Barzun in his magisterial From Dawn to Decadence: 1500 to the Present: 500 Years of Western Cultural Life (2000).

Science nowadays plays much the same societal role as the Roman Catholic Church did in Western Civilization before the Reformation and the Enlightenment. The Church had become corrupted through bureaucracy and self-interest and the dysfunctions that arise inevitably as a result of human failings when an activity becomes too big and too powerful. It became obvious that the Church’s policies and actions had grown seriously at variance with its founding ideals. The Reformation and the Enlightenment brought and demonstrated the benefits of empirical, rational, evidence-based, pragmatism in the search for reliable understanding, by contrast to taking for granted what the authorities said.

Today’s scientific activity has become similarly dysfunctional through growing too big and too influential; something like a Science Court is needed to bring society the benefits of empirical, rational, evidence-based, pragmatism in the search for reliable insights.

 

Please note that I am far from alone in noting the dysfunctions of contemporary science and medicine: consider the many books, articles, and reports listed in these bibliographies:
http://henryhbauer.homestead.com/CRITIQUES_OF_CONTEMPORARY_SCIENCE_AND_MEDICINE.pdf
http://henryhbauer.homestead.com/WhatIsWrongWithMedicine.pdf

Posted in conflicts of interest, consensus, denialism, global warming, media flaws, medical practices, politics and science, prescription drugs, science is not truth, science policy | Tagged: | 2 Comments »

HPV does not cause cervical cancer; HPV vaccination can be deadly

Posted by Henry Bauer on 2018/09/16

Evidence continues to mount that the presumed connection between HPV and cervical cancer is no more than a statistical association, not a causative relationship:

The Gardasil controversy: as reports of adverse effects increase, cervical cancer rates rise in HPV-vaccinated age groups 

Annette Gartland

“The Gardasil vaccines continue to be vaunted as life-saving, but there is no evidence that HPV vaccination is reducing the incidence of cervical cancer, and reports of adverse effects now total more than 85,000 worldwide. Nearly 500 deaths are suspected of being linked to quadrivalent Gardasil or Gardasil 9.
As Merck’s latest human papillomavirus (HPV) vaccine, Gardasil 9, continues to be fast tracked around the world, the incidence of invasive cervical cancer is increasing in many of the countries in which HPV vaccination is being carried out.”

Once again independent scientists without conflicts of interest are maltreated by bureaucratic organizations with conflicts of interest to commercial interests, drug companies in particular:

“This article was updated with information from the AHVID on 14/09/2018.
Update 15/9/2018:
Peter Gøtzsche has been expelled from the Cochrane Collaboration. Six of the 13 members of the collaboration’s governing board voted for his expulsion.
. . . . .
‘This is the first time in 25 years that a member has been excluded from membership of Cochrane. This unprecedented action taken by a minority of the governing board . . . . ‘
In just 24 hours, Gøtzsche said, the Cochrane governing board had lost five of its members, four of whom were centre directors and key members of the organisation in different countries.
Gøtzsche says that, in recent years, Cochrane has significantly shifted more to a profit-driven approach.
‘Even though it is a not-for-profit charity, our ‘brand’ and ‘product’ strategies are taking priority over getting out independent, ethical and socially responsible scientific results,’ he said'”.

 

 

Posted in conflicts of interest, fraud in medicine, fraud in science, medical practices, prescription drugs, unwarranted dogmatism in science | Tagged: , , , , | Leave a Comment »

What everyone ought to know about global warming and climate change: an unbiased review

Posted by Henry Bauer on 2018/09/11

“What everyone knows” is that burning fossil fuels releases carbon dioxide, a “greenhouse gas” that holds in heat, warming the Earth and causing climate change, with catastrophic consequences if it isn’t stopped soon.

All official agencies, all mainstream scientific groups, say that.

What few people know is that a considerable number of experts and informed observers do not believe this AGW scenario to be correct: AGW = Anthropogenic Global Warming, global warming caused by human actions.

Those dissenting experts point out that actual data on temperature and carbon-dioxide levels, over the life of the Earth but also over the last century, show that carbon dioxide does not cause high global temperature.

But few people, again, can believe that “everyone” could be wrong about this, that “science” could be so dogmatically wrong. To form an opinion as to the relative merits of the official view and of the dissenting experts, therefore requires not only looking at the data but also at how the official view came into bring and how and why it persists. Few people want to take the time and make the effort to wade through huge amounts of writings by opposing advocates to ferret out the genuine facts and legitimate conclusions, which often calls for reading between the lines and being skeptical about everything.

My recent discovery of the Peter Ridd affair had a wonderfully beneficial consequence, learning about the writings of Don Aitkin, an Australian whose academic career included research on social and political matters as well as administrative experience that included heading a university (as Vice-Chancellor and President of the University of Canberra). Aitkin spent a decade or more reading and thinking about AGW, and summarized what he learned in a series of blogs. The last in the series, #16,  sums things up and has appropriate links to the earlier ones which concentrate on different aspects of the matter.

This offers a wonderfully convenient way for anyone to become genuinely informed about AGW, and “climate-change denialism”, and incidentally about the interaction between science and public policy. Aitkin is factually reliable and ideologically unbiased, an all-too-rare combination.

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My appreciation of Aitkin’s series on global warming was enhanced when he noted that the hysteria over AGW “bridges the space between science and politics in an almost unprecedented way, though it has some similarities to the ‘eugenics’ issue a hundred years ago”, something that had occurred to me also.

Another Aitkin blog-post, “A good starting position in discussions about ‘climate change’” cites the salient points made by Ben Pile at Climate Resistance:

  1. There is good scientific evidence that human activities are influencing the climate. But evidence is not fact, and neither evidence nor fact speak for themselves.
  2. The evidence for anthropogenic climate change is neither as strong nor as demanding of action as is widely claimed.
  3. Our ability to mitigate, let alone to reverse, any such change through reductions in CO2 emissions is even less certain, and may itself be harmful.
  4. The scientific consensus on climate change as widely reported inaccurately reflects the true state of scientific knowledge.
  5. How society should proceed in the face of a changing climate is the business of politics not science.
  6. Political arguments about climate change are routinely mistaken for scientific ones. Environmentalism uses science as a fig-leaf to hide an embarrassment of blind faith and bad politics.
  7. Science is increasingly expected to provide moral certainty in morally uncertain times.
  8. The IPCC is principally a political organisation.
  9. The current emphasis on mitigation strategies is impeding society’s ability to adapt to a changing climate, whatever its cause.
  10. The public remains unconvinced that mitigation is in its best interest. Few people have really bought into Environmentalism, but few people object vehemently to it. Most people are slightly irritated by it.
  11. And yet climate change policies go unchallenged by opposition parties.
  12. Environmentalism is a political ideology, yet it has never been tested democratically.
  13. Widespread disengagement from politics means that politicians have had to seek new ways to connect with the public. Exaggerated environmental concern is merely serving to provide direction for directionless politics.
  14. Environmentalism is not the reincarnation of socialism, communism or Marxism. It is being embraced by the old Right and Left alike. Similarly, climate change scepticism is not the exclusive domain of the conservative Right.
  15. Environmentalism will be worse for the poor than climate change.
  16. Environmentalism is a self-fulfilling prophecy.

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Aitkin is an Australian, and any connection to Australia always rekindles my appreciation for the sanctuary Australia provided the refuigee Bauers and the excellent public education from which I benefited in elementary school (Picton, NSW), at The Sydney Boys’ High School, and at the University of Sydney (moreover, in those years, at almost no cost to my parents!).
Browsing Aitkin’s writings, I came across an after-dinner speech about “Australian values”  that rings true to my own recollections and also, I think, offers some insights into the similarities and differences between American and Australian life.

Posted in conflicts of interest, consensus, denialism, funding research, global warming, media flaws, peer review, politics and science, resistance to discovery, science is not truth, science policy, scientific culture, scientific literacy, scientism, scientists are human, unwarranted dogmatism in science | Tagged: , , | 3 Comments »

Australian university fires climate-change dissenter: dissent is not collegial…

Posted by Henry Bauer on 2018/09/08

Just another bit of evidence of politically correct dogmatism in science; see Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth, McFarland 2012

Tenured professor Peter Ridd, a marine scientist, was fired from James Cook University (Queensland, Australia), for sharing with a journalist his view that certain published work is misleading:

“Ridd’s expertise is in coastal oceanography and the impact of sediments on reefs and, for years, he has criticised research suggesting the Great Barrier reef is in serious trouble due to global warming and agricultural run-off, among other things. He claims the research lacks quality assurance, isn’t replicated often enough, and that the peer review system for research is inadequate. . . .
His trouble started in April 2016 when he received a ‘formal censure’ for ‘misconduct’. It was a curious incident: the university had got hold of an email that Ridd sent to a news.com.au journalist a few months before. In it, he urged the journalist to look into work Ridd had done suggesting that photographs released by the Great Barrier Reef Marine Park Authority indicating a big decline in reef health over time were misleading …
the ARC Centre of Excellence for Coral Reef Studies – based at James Cook University –‘should check their facts before they spin their story . . .’

This was enough for the university to censure Ridd on the grounds that he breached the code of conduct by ‘going to the media in your professional capacity in a way that was not collegial and did not respect the rights of others or uphold professional standards’. It was a warning. Ridd could make public comments but they ‘must be in a collegial manner that upholds the university and individuals’ respect’”.

In other words, don’t offer evidence that contradicts the mainstream view, especially if there are mainstream proponents in your own university.

Academic freedom to teach and publish?

Open-minded science that respects evidence?

Read the full article in The Guardian: Gay Alcorn, “Peter Ridd’s sacking pushes the limit of academic freedom”. Note that the journalist, Alcorn, takes human-caused climate change as Gospel truth, yet recognizes that the University fired Ridd because he sought media prominence for his views and refused to allow himself to be censored into not speaking publicly about the University’s actions against him. The Guardian, a stalwart supporter of left-leaning political correctness, could not quite bring itself to state straightforwardly that the university stepped way over the line as to academic freedom, but that’s a minor quibble; I congratulate Gay Alcorn and The Guardian for straight, unbiased reporting.

Ridd has sued the University and raised funds for his legal costs though crowd-funding; “the court hearing has been set for 12, 13 and 14th November”.

Posted in conflicts of interest, consensus, denialism, funding research, global warming, legal considerations, media flaws, politics and science, unwarranted dogmatism in science | Tagged: , , , , , | 2 Comments »

21st century science:   Group-Thinking Elites and Fanatical Groupies

Posted by Henry Bauer on 2018/08/11

Science has been a reliable resource for official policies and actions for much of the era of modern science, which is usually regarded as having begun around the 17th century.

It is almost without precedent that a mistaken scientific consensus should lead to undesirable and damaging public actions, yet that is now the case in two instances: the belief that carbon dioxide generated by the burning of fossil fuels is primarily responsible for global warming and climate change; and the belief that HIV is the cause of AIDS.

Both those beliefs gained hegemony during the last two or three decades. That these beliefs are mistaken seems incredible to most people, in part because of the lack of any well known precedent and in part because the nature of science is widely misunderstood; in particular it is not yet widely recognized how much science has changed since the middle of the 20th century.

The circumstances of modern science that conspire to make it possible for mistaken theories to bring misguided public policies have been described in my recent book, Science Is Not What You Think [1]. The salient points are these:

Ø     Science has become dysfunctionally large

Ø     It is hyper-competitive

Ø     It is not effectively self-correcting

Ø     It is at the mercy of multiple external interests and influences.

A similar analysis was offered by Judson [2]. That title reflects the book’s opening theme of the prevalence of fraud in modern science (as well as in contemporary culture). It assigns blame to the huge expansion in the number of scientists and the crisis that the world of science faces as it finds itself in something of a steady-state so far as resources are concerned, after a period of some three centuries of largely unfitted expansion: about 80% of all the scientists who have ever lived are extant today; US federal expenditure on R&D increased 4-fold (inflation-adjusted!) from 1953 to 2002, and US industry increased its R&D spending by a factor of 26 over that period! Judson also notes the quintessential work of John Ziman explicating the significance of the change from continual expansion to what Ziman called a dynamic steady-state [3].

Remarkably enough, President Eisenhower had foreseen this possibility and warned against it in his farewell address to the nation: “in holding scientific research and discovery in respect, as we should, we must also be alert to the equal and opposite danger that public policy could itself become the captive of a scientific-technological elite”. The proponents of human-caused-climate-changer theory and of HIV/AIDS theory are examples of such elites.

A crucial factor is that elites, like all other groups, may be dysfunctionally affected by the phenomenon of Groupthink.

Janis [4] showed in detail several decades ago how that phenomenon of Groupthink had produced disastrously bad policy actions by the United States. The same phenomenon of Groupthink can cause bad things to happen in other social sectors than the government. Recently, Booker [5] has shown how Groupthink has been responsible for creating the worldwide belief, shibboleth, cliché, that humankind’s use of fossil fuels is causing global warming and climate change through the release of carbon dioxide.

Commonly held ideas about science do not envisage the possibility that a scientific consensus could bring misguided policies and actions on a global scale. What most people know — think they know — about science is that its conclusions are based on solid evidence, and that the scientific method safeguards against getting things wrong, and that science that has been primarily responsible for civilization’s advances over the last few centuries.

Those things that most people know are also largely mistaken [1, 6]. Science is a human activity and is subject to all the frailties and fallibilities of any human activity. The scientific method and the way in which it is popularly described does not accurately portray how science is actually done.

While much of the intellectual progress in understanding how the world works does indeed stand to the credit of science, what remains to be commonly realized is that since about the middle of the 20th century, science has become too big for its own good. The huge expansion of scientific activity since the Second World War has changed science in crucial ways. The number of people engaged in scientific activity has far outstripped the available resources, leading to hyper-competition and associated sloppiness and outright dishonesty. Scientists nowadays are in no way exceptional individuals, people doing scientific work are as common as are teachers, doctors, or engineers. It is in this environment that Groupthink has become significantly and damagingly important.

Booker [5] described this in relation to the hysteria over the use of fossil fuels. A comparable situation concerns the belief that HIV is the cause of AIDS [7]. The overall similarities in these two cases are that a quite small number of researchers arrived initially at more or less tentative conclusions; but those conclusions seemed of such great import to society at large that they were immediately seized upon and broadcast by the media as breaking news. Political actors become involved, accepting those conclusions quickly became politically correct, and those who then questioned and now question the conclusions are vigorously opposed, often maligned as unscientific and motivated by non-scientific agendas.

 

At any rate, contemporary science has become a group activity rather than an activity of independent intellectual entrepreneurs, and it is in this environment that Groupthink affects the elites in any given field — the acknowledged leading researchers whose influence is entrenched by editors and administrators and other bureaucrats inside and outside the scientific community.

A concomitant phenomenon is that of fanatical groupies. Concerning both human-caused climate change and the theory that HIV causes AIDS, there are quite large social groups that have taken up the cause with fanatical vigor and that attack quite unscrupulously anyone who differs from the conventional wisdom. These groupies are chiefly people with little or no scientific background, or whose scientific ambitions are unrequited (which includes students). As with activist groups in general, groupie organizations are often supported by (and indeed often founded by) commercial or political interests. Non-profit organizations which purportedly represent patients and other concerned citizens and which campaign for funds to fight against cancer, multiple sclerosis, etc., are usually funded by Big Pharma, as are HIV/AIDS activist groups.

__________________________________

[1]  Henry H. Bauer, Science Is Not What You Think — how it has changed, why we can’t trust it, how it can be fixed, McFarland 2017

[2] Horace Freeland Judson, The Great Betrayal, Harcourt 2004

[3]  John Ziman, Prometheus Bound, Cambridge University Press 1994

[4]  I. L. Janis, Victims of Groupthink, 1972; Groupthink, 1982, Houghton Mifflin.

[5]  Christopher Booker, GLOBAL WARMING: A case study in groupthink, Global Warming Policy Foundation, Report 28; Human-caused global warming as Groupthink

[6]  Henry H. Bauer, Scientific Literacy and Myth of the Scientific Method, University of Illinois Press 1992

[7]  Henry H. Bauer, The Origin, Persistence and Failings of HIV/AIDS Theory, McFarland 2007

Posted in conflicts of interest, consensus, fraud in science, funding research, global warming, media flaws, science is not truth, science policy, scientific culture, scientific literacy, scientism, scientists are human, the scientific method, unwarranted dogmatism in science | Tagged: , , | Leave a Comment »

Who guards the guardians? Who guards science?

Posted by Henry Bauer on 2018/06/24

Quis custodiet ipsos custodes? This quotation attributed to Juvenal describes the inescapable dilemma as to how societies can be governed .

Today’s guardian of reliable knowledge is science. It is the acknowledged authority on the natural world, on what exists in the world and on how those things behave. Most governments accept as reliable, as true for all practical purposes, whatever the current scientific consensus is: on matters of health, the environment, the solar system, the universe. The mass media, too, accept that scientific consensus; and that largely determines what the general public believes, “what everyone knows”.

Nowadays in that category of “what everyone knows” there are literally innumerable things; among them that the universe began with a Big Bang; that ghosts and Loch Ness Monsters do not exist; that HIV causes AIDS; that hypertension causes heart attacks and strokes; that carbon dioxide released by burning fossil fuels is causing climate change and bringing more frequent and more extreme and more damaging events like hurricanes; etc., etc.

But what guards against the scientific consensus being wrong?

Nothing and nobody.

That really matters, because the history of science is crystal clear that contemporary science, the contemporary scientific consensus, has almost invariably been wrong until further progress superseded and replaced it.

That steady improvement over the centuries gave rise to a comforting shibboleth, that “science is self-correcting”. At any given moment, however, the scientific consensus stands possibly uncorrected and awaiting future “self”-correction. One cannot justifiably assert, therefore, that any contemporary scientific consensus is known to be unquestionably true. It is not known with absolute certainty that the universe began with a Big Bang; that ghosts and Loch Ness Monsters do not exist; that HIV causes AIDS; that hypertension causes heart attacks and strokes; that carbon dioxide released by burning fossil fuels is causing climate change and bringing more frequent and more extreme and more damaging events like hurricanes; etc., etc.

Nevertheless, contemporary society treats these and other contemporary scientific consensuses as true. This amounts to what President Eisenhower warned against: that “public policy could itself become the captive of a scientific-technological elite” [1]. Science can indeed mislead public policy, as when tens of thousands of Americans were forcibly sterilized in the misguided belief that this improved the genetic stock [2]. Science is far from automatically or immediately self-correcting [3].

I’ve wondered how Eisenhower could have been so prescient in 1960, because the conditions that conduce to public policies being misled by science were then just beginning to become prominent: the massive governmental stimulation of scientific activity that has produced today’s dysfunctional hyper-competitiveness, with far too many would-be researchers competing for far too few reliably permanent positions and far too little support for the resources that modern research needs [4]. Moreover, the scientific consensus is guarded not only by the scientists who generated it, powerful societal institutions are vested in the correctness of the scientific consensus [4]: It is virtually inconceivable, for instance, that official bodies like the National Institutes of Health, the Food and Drug Administration, the Centers for Disease Control & Prevention, the World Health Organization, and the like would admit to error of the views that they have promulgated; try to imagine, for example, how it could ever be officially admitted that HIV does not cause AIDS [5].

SUGGESTION TO THE READER:
Reflect on how you formed an opinion about — Big-Bang theory? Loch Ness Monsters? Ghosts? Climate change? … etc. etc. Almost always it will not have been by looking into the evidence but rather by trusting someone’s assertion.

Who has the interest, time, and energy to study all those things? Obviously we must take our beliefs on many matters from trusted authorities; and for a couple of centuries the scientific consensus has been a better guide than most others. But that is no longer the case. The circumstances of 21st-century science mean that society needs guardians to check that what the scientific consensus recommends for public policy corresponds to the best available evidence. On many issues, a minority of experts differs from the scientific consensus, and it would be valuable to have something like a Science Court to assess the arguments and evidence pro and con [6].

I’ve had the luxury of being able to look into quite a few topics because that was appropriate to the second phase of my academic career, in Science & Technology Studies (STS). Through having made a specialty of studying unorthodoxy in science, I stumbled on copious examples of the scientific consensus treating, in recent times, competent minority opinions well within the scientific community with the same disdain, or even worse, as that traditionally directed towards would-be science, fringe science — Loch Ness Monsters, ghosts, UFOS, and the like.

In Dogmatism in Science and Medicine [7], I pointed to the evidence that the contemporary scientific consensus is wrong about Big-Bang theory, global warming and climate change, HIV/AIDS, extinction of the dinosaurs, and more, including what modern medicine says about prescription drugs. The failings of the scientific consensus in modern medicine have been detailed recently by Richard Harris [8] as well as in many works of the last several decades [9]. That the scientific consensus is wrong about HIV and AIDS is documented more fully in The Origin, Persistence and Failings of HIV/AIDS Theory (McFarland, 2007). Why science has become less believable is discussed in [4], which also describes many misconceptions about science and about statistics, the latter bearing a large part of the blame for what’s wrong with today’s medical practices.

But my favorite obsession over where the scientific consensus is wrong remains the existence of Loch Ness “Monsters”, Nessies. It was my continuing curiosity about this that led to my career change from chemistry to STS, which brought many unforeseeable and beneficial side-effects. My 1986 book, The Enigma of Loch Ness: Making Sense of a Mystery [10], showed how the then-available evidence could be interpreted to support belief in the reality of Nessies but could also be plausibly enlisted to reject the reality of Nessies. However, the book’s chief purpose was to explain why seeking to “discover” Nessies was not a sensible task for organized science.

Now in 2018 quite proper science, in the guise of “environmental DNA”, has offered a good chance that my belief in the reality of Loch Ness “Monsters” may be vindicated within a year or so by mainstream science. I plan to say more about that soon.

—————————————————————–

[1]  Farewell Address to the Nation, 17 January 1961
[2]  “Bauer: Could science mislead public policy?”
[3]  Science is NOT self-correcting (How science has changed — VII)
[4]  Science Is Not What You Think — how it has changed,
why we can’t trust it, how it can be fixed
(McFarland, 2017)
[5]   “OFFICIAL!   HIV does not cause AIDS!”
[6]    For a detailed history and analysis of the concept of a Science Court,
see chapter 12 in [4]
[7]    Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth (McFarland, 2012)
[8]    Richard Harris, Rigor Mortis — How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions (Basic Books, 2017)
[9]    What’s Wrong with Present-Day Medicine, a bibliography last updated 17 April 2017
[10]  The Enigma of Loch Ness: Making Sense of a Mystery, University of Illinois Press, 1986;
in Cassette Book format, RC 25592, narrated by Richard Dorf, 1988;
U.K. edition, Stirling (Scotland): Johnston & Bacon 1991;
re-issued by Wipf & Stock, 2012

Posted in conflicts of interest, consensus, funding research, global warming, media flaws, medical practices, peer review, politics and science, prescription drugs, resistance to discovery, science is not truth, science policy, unwarranted dogmatism in science | Tagged: | 3 Comments »

Science is NOT self-correcting (How science has changed — VII)

Posted by Henry Bauer on 2018/05/06

One of the common and popular shibboleths about science is that it is self-correcting. That implies happening inevitably and automatically. But despite the existence of innumerable scientific organizations and institutions, there is no overarching system or set of protocols or hierarchy that governs all scientific activity. Nothing about scientific activity is automatic or inevitable.

The illusion of self-correction may trace back to the fact that science has surely progressed over time, to better and deeper understanding of how the world works, superseding and rejecting mistakes and misunderstandings. However, this correcting of earlier mis-steps was never automatic; more important, it was never a sure thing. Barber [1] surveyed the long history of hegemonic scientific consensuses vigorously resisting correction. Stent [2] described the phenomenon of “premature discovery” whereby some hegemonic scientific consensuses have forestalled correction for decades — about 40 years with Mendel’s quantitative insight into heredity, about half a century with Wegener’s insight into continental movements.

Barber and Stent dealt with the more-or-less classic modern science that subsisted up until about the middle of the 20th century, the sort of science whose ethos could be fairly adequately described by the Mertonian Norms [3]; a cottage industry of independent, voluntarily cooperating, largely disinterested ivory-tower intellectual entrepreneurs in which science was free to do its own thing, seeking truths about the natural world. Individuals were free to publish their results with little or no hindrance. There were plenty of journals and plenty of journal space, and editors were keen to receive contributions: “From the mid-1800s, there was more journal space than there were articles . . . . assistant editors [had the] . . . primary responsibility . . . to elicit articles and reviews to fill the pages of the publication” [4].

The onus for ensuring that published work was sound rested on the authors, there was not the contemporary gauntlet of “peer reviewers” to run: “for most of the history of scientific journals, it has been editors — not referees — who have been the key decision-makers and gatekeepers. . . . It was only in the late 20th century that refereeing was rebranded as ‘peer review’ and acquired (or reacquired) its modern connotation of proof beyond reasonable doubt. . . . A Google ngram — which charts yearly frequencies of any phrase in printed documents — makes the point starkly visible: it was in the 1970s that the term ‘peer review’ became widely used in English. [We] . . . do not yet know enough about why the post-war expansion of scientific research . . . led to . . . ‘peer review’ [coming] . . . to dominate the evaluation of scholarly research” [5].

Nowadays, by contrast, where publication makes a career and lack of publication means career failure, journals are swamped with submissions at the same time as costs have exploded and libraries are hard pressed to satisfy their customers’ wishes for everything that gets published. Journals are now ranked in prestige by how small a proportion of submissions they accept, and “peer review” is pervaded by conflicts of interest. The overall consequence is that the “leading journals” hew to the current “scientific consensus” so that unorthodoxies, radical novelties, minority views find it difficult to get published. How extreme can be the efforts of “the consensus” to suppress dissent has been profusely documented on a number of topics, including the very publicly visible issues of HIV/AIDS and climate change [6, 7, 8].

Where the consensus happens to be in need of “self-correction”, in other words, today’s circumstances within the scientific community work against any automatic or easy or quick correction.

That situation is greatly exacerbated by the fact that correction nowadays is no simple revising of views within the scientific community. “Science” has become so entwined with matters of great public concern that particular beliefs about certain scientific issues have large groups of influential supporters outside the scientific community who seek actively to suppress dissent from “the consensus”; over HIV/AIDS, those groupies who abet the consensus include the pharmaceutical industry and activist organizations largely supported by drug companies; over climate change, environmentalists have seized on “carbon emissions” as a weapon in their fight for sustainability and stewardship of nature.

Science is not inevitably or automatically self-correcting. Its official agencies, such as the Food and Drug Administration, the Centers for Disease Control & Prevention, the National Institutes of Health, the World Health Organization, etc., are captives of the contemporary scientific consensus and thereby incapable of drawing on the insights offered by minority experts, which is also the case with the peer-review system and the professional journals.

Even when outright fraud or demonstrated honest mistakes have been published, there is no way to ensure that the whole scientific community becomes aware of subsequent corrections or retractions, so errors may continue to be cited as though they were reliable scientific knowledge. Even the journals regarded as the most reliable (e.g. Nature journals, Cell, Proceedings of the National Academy) make it quite difficult for retractions or corrections to be published [9], and even complete retraction seemed to reduce later citation by only about one-third, very far from “self-correcting” the whole corpus of science [10].

 

==========================================

[1]    Bernard Barber, “Resistance by scientists to scientific discovery”, Science, 134 (1961) 596–602

[2]    Gunther Stent, “Prematurity and uniqueness in scientific discovery”, Scientific American, December 1972, 84–93

[3]    How science has changed — II. Standards of Truth and of Behavior

[4]    Ray Spier, “The history of the peer-review process”, TRENDS in Biotechnology, 20 (2002) 357-8

[5]    Aileen Fyfe, “Peer review: not as old as you might think”, 25 June 2015

[6]    Henry H. Bauer, The Origin, Persistence and Failings of HIV/AIDS Theory, McFarland, 2007

[7]    Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth, McFarland, 2012

[8]    Science Is Not What You Think: How It Has Changed, Why We Can’t Trust It, How It Can Be Fixed (McFarland 2017)

[9]    “Science is self-correcting” (ed.) Lab Times, 2012. #1: 3

[10]  Mark P. Pfeifer & Gwendolyn L. Snodgrass, “The continued use of retracted, invalid scientific literature”, JAMA, 263 (1990) 1420-3)

 

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How science changed — IV. Cutthroat competition and outright fraud

Posted by Henry Bauer on 2018/04/15

The discovery of the structure of DNA was a metaphorical “canary in the coal mine”, warning of the intensely competitive environment that was coming to scientific activity. The episode illustrates in microcosm the seismic shift in the circumstances of scientific activity that started around the middle of the 20th century [1], the replacement of one set of unwritten rules by another set [2].
The structure itself was discovered by Watson and Crick around 1950, but it was only in 1968, with the publication of Watson’s personal recollections, that attention was focused on how Watson’s approach and behavior marked a break from the traditional unwritten rules of scientific activity.
It took even longer for science writers and journalists to realize just how cutthroat the competition had become in scientific and medical research. Starting around 1980 there appeared a spate of books describing fierce fights for priority on a variety of specific topics:
Ø    The role of the brain in the release of hormones; Guillemin vs. Schally — Nicholas Wade, The Nobel Duel: Two Scientists’ 21-year Race to Win the World’s Most Coveted Research Prize, Anchor Press/Doubleday, 1981.
Ø    The nature and significance of a peculiar star-like object — David H. Clark, The Quest for SS433, Viking, 1985.
Ø    “‘Mentor chains’, characterized by camaraderie and envy, for example in neuroscience and neuropharmacology” — Robert Kanigel, Apprentice to Genius: The Making of a Scientific Dynasty, Macmillan, 1986.
Ø    High-energy particle physics, atom-smashers — Gary Taubes, Nobel Dreams: Power, Deceit, and the Ultimate Experiment, Random House, 1986.
Ø    “Soul-searching, petty rivalries, ridiculous mistakes, false results as rivals compete to understand oncogenes” — Natalie Angier, Natural Obsessions: The Search for the Oncogene, Houghton Mifflin, 1987.
Ø    “The brutal intellectual darwinism that dominates the high-stakes world of molecular genetics research” — Stephen S. Hall, Invisible Frontiers: The Race to Synthesize a Human Gene, Atlantic Monthly Press, 1987.
Ø    “How the biases and preconceptions of paleoanthropologists shaped their work” — Roger Lewin, Bones of Contention: Controversies in the Search for Human Origins, Simon & Schuster, 1987.
Ø    “The quirks of . . . brilliant . . . geniuses working at the extremes of thought” — Ed Regis, Who Got Einstein’s Office: Eccentricity and Genius at the Institute for Advanced Study, Addison-Wesley, 1987.
Ø    High-energy particle physics — Sheldon Glashow with Ben Bova, Interactions: A Journey Through the Mind of a Particle Physicist and the Matter of the World, Warner, 1988.
Ø    Discovery of endorphins — Jeff Goldberg, Anatomy of a Scientific Discovery, Bantam, 1988.
Ø    “Intense competition . . . to discover superconductors that work at practical temperatures “ — Robert M. Hazen, The Breakthrough: The Race for the Superconductor, Summit, 1988.
Ø    Science is done by human beings — David L. Hull, Science as a Process, University of Chicago Press, 1988.
Ø    Competition to get there first — Charles E. Levinthal, Messengers of Paradise: Opiates and the Brain, Anchor/Doubleday 1988.
Ø    “Political machinations, grantsmanship, competitiveness” — Solomon H. Snyder, Brainstorming: The Science and Politics of Opiate Research, Harvard University Press, 1989.
Ø    Commercial ambitions in biotechnology — Robert Teitelman, Gene Dreams: Wall Street, Academia, and the Rise of Biotechnology, Basic Books, 1989.
Ø    Superconductivity, intense competition — Bruce Schechter, The Path of No Resistance: The Story of the Revolution in Superconductivity, Touchstone (Simon & Schuster), 1990.
Ø    Sociological drivers behind scientific progress, and a failed hypothesis — David M. Raup, The Nemesis Affair: A Story of the Death of Dinosaurs and the Ways of Science, Norton 1999.

These titles illustrate that observers were able to find intense competitiveness wherever they looked in science; though mostly in medical or biological science, with physics including astronomy the next most frequently mentioned field of research.
Watson’s memoir had not only featured competition most prominently, it had also revealed that older notions of ethical behavior no longer applied: Watson was determined to get access to competitors’ results even if those competitors were not yet anxious to reveal all to him [3]. It was not only competitiveness that increased steadily over the years; so too did the willingness to engage in behavior that not so long before had been regarded as improper.
Amid the spate of books about how competitive research had become, there also was published. Betrayers of the Truth: Fraud and Deceit in the Halls of Science by science journalists William Broad and Nicholas Wade (Simon & Schuster, 1982). This book argued that dishonesty has always been present in science, citing in an appendix 33 “known or suspected” cases of scientific fraud from 1981 back to the 2nd century BC. These actual data could not support the book’s sweeping generalizations [4], but Broad and Wade had been very early to draw attention to the fact that dishonesty in science was a significant problem. What they failed to appreciate was why: not that there had always been a notable frequency of fraud in science but that scientific activity was changing in ways that were in process of making it a different kind of thing than in the halcyon few centuries of modern science from the 17th century to the middle of the 20th century.
Research misconduct had featured in Congressional Hearings as early as 1981. Soon the Department of Health and Human Services established an Office of Scientific Integrity, now the Office of Research Integrity. Its mission is to instruct research institutions about preventing fraud and dealing with allegations of it. Scientific periodicals began to ask authors to disclose conflicts of interest, and co-authors to state specifically what portions of the work were their individual responsibility.
Academe has proliferated Centers for Research and Medical Ethics [5], and there are now periodicals entirely devoted to such matters [6]. Courses in research ethics have become increasingly common; it is even required that such courses be available at institutions that receive research funds from federal agencies.
In 1989, the Committee on the Conduct of Science of the National Academy of Sciences issued the booklet On Being a Scientist, which describes proper behavior; that booklet’s 3rd edition, titled A Guide to Responsible Conduct in Research, makes even clearer that the problem of scientific misconduct is now widely seen as serious.
Another indication that dishonesty has increased is the quite frequent retraction of published research reports: Retraction Watch estimates that 500-600 published articles are retracted annually. John Ioannidis has made a specialty of reviewing literature for consistency, and reported: “Why most published research findings are false” [7]. Nature has an archive devoted to this phenomenon [8].

Researchers half a century ago would have been aghast and disbelieving at all this, that science could have become so untrustworthy. It has happened because science changed from an amateur avocation to a career that can bring fame and wealth [9]; and scientific activity changed from a cottage industry to a highly bureaucratic corporate industry, with pervasive institutional as well as individual conflicts of interest; and researchers’ demands for support have far exceeded the available supply.

And as science changed, it drew academe along with it. More about that later.

===============================================

[1]    How science changed — III. DNA: disinterest loses, competition wins
[2]    How science has changed— II. Standards of Truth and of Behavior
[3]    The individuals Watson mentioned as getting him access corrected his recollections: they shared with him nothing that was confidential. The significant point remains that Watson had no such scruples.
[4]    See my review, “Betrayers of the truth: a fraudulent and deceitful title from the journalists of science”, 4S Review, 1 (#3, Fall) 17–23.
[5]   There is an Online Ethics Center for Engineering and Science. Physical Centers have been established at: University of California, San Diego (Center for Ethics in Science and Technology); University of Delaware (Center for Science, Ethics and Public Policy); Michigan State University (Center for Ethics and Humanities in the Life Sciences); University of Notre Dame (John J. Reilly Center for Science, Technology, and Values).
[6]    Accountability in Research (founded 1989); Science and Engineering Ethics (1997); Ethics and Information Technology (1999); BMC Medical Ethics (2000); Ethics in Science and Environmental Politics (2001).
[7]    John P. A. Ioannidis, “Why Most Published Research Findings Are False”, PLoS Medicine, 2 (2005): e124. 
[8]    “Challenges in irreproducible research”
[9]    How science has changed: Who are the scientists?

Posted in conflicts of interest, fraud in medicine, fraud in science, funding research, media flaws, science is not truth, scientific culture, scientists are human | Tagged: , | Leave a Comment »

 
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