Skepticism about science and medicine

In search of disinterested science

Archive for the ‘peer review’ Category

CoVID19: what do we really know?

Posted by Henry Bauer on 2020/09/15

A visitor to my website sent me this email:

“Hello Dr Bauer. I just read your 2002 article on Confessions of an AIDS Denialist. . . . You must have a lot to say about COVID-19! I . . . would be interested in your view.”

I suspect that my reply will have been rather disappointing:

“I had a lot of fairly reliable data about AIDS and HIV, but there’s a great lack of sound, reliable data about the present circumstances.

AIDS was first noticed and named in the early 1980s, and I looked into it seriously some 20 years later. With CoVID-19, even well-informed experts have been revising their views steadily as more information comes in.

At least one thing is clear already, thanks in part to what has been learned about HIV/AIDS: There is no reliable gold-standard test for diagnosing infection by the supposed coronavirus. HIV/AIDS can be blamed for that because it was with HIV that virologists first allowed the medical profession to use antibody tests and PCR tests as diagnostic of infection even as the published peer-reviewed mainstream literature stated quite clearly that these tests could not establish the presence of infection and should not be used for diagnosis.

The reason is that pure virions, particles of HIV, have never been isolated direct from an AIDS patient.

CoVID-19 infection is being diagnosed on the basis of PCR tests without isolation of actual virus. Even if the bits of RNA or DNA being picked up by PCR could be known to be like some components of a coronavirus, that would not demonstrate that they actually originated from particles of such a virus. As De Harven  had pointed out with respect to HIV tests, what PCR picks up might come from random circulating pieces of DNA or RNA or from the expression of human endogenous retroviruses (HERVs).

I think John Ioannidis Is trying honestly and without preconceptions or conflicts of interest to understand CoVID-19, and he is eminently qualified to do so. His most recent analysis  suggests that the virulence of CoVID-19 is comparable to that of the respiratory virus(es) underlying really bad so-called flu seasons.

The numbers that are being thrown around in the mass media are more misleading than informative. For instance, numbers of cases are continually reported and publicized as disastrous without any information about the symptomatic levels of those cases.

In my view, the clearest indication that deaths can be ascribed to the influence of a novel coronavirus is the data on excess all-cause deathshttps://www.cdc.gov/nchs/nvss/vsrr/covid19/excess_deaths.htm

https://www.euromomo.eu/graphs-and-maps

Both in Europe and in the United States, it seems that 2020 is definitely worse than the bad flu season of 2018.

The comparative data for European countries do not yield obvious information about the best way of handling the present infectious agent.

I think that one more thing is, however, quite clear: we do not properly understand why excess deaths are typically somewhat higher during “flu seasons”. Is it simply that when the weather becomes more wintry, mortality increases? Of course particularly among those who are the least healthy, which tends to be among those of greater age? Do respiratory viruses play a significant role in this? If so, should some of the measures now being advocated also be practiced during all winter seasons? What is the actual efficacy, if any, of vaccinating against flu?

I do not subscribe to the conspiracy theories that regard the pandemic as planned by governments, agencies, and corporations (e.g. the Gates Foundation) as a step toward increasing domination and control of the general population. I do believe very strongly, however, that the circumstances are being made considerably worse for most people through deliberate actions of pharmaceutical companies, associated conflicts of interest among legislatures and executives, and widespread general incompetence, together with the lack of an impartial, authoritative source of scientific knowledge and understanding.

A sad lesson from HIV/AIDS is that official agencies dealing with medicine in general and virology in particular are not truly competent. Anthony Fauci, Robert Redfield, the CDC as a whole, the World Health Organization, etc., continue to be quite wrong about HIV/AIDS. And the approval of drugs and medical devices is incompetent or corrupt or both, and is no safeguard against products pushed by the pharmaceutical companies even when their potential benefits are greatly outweighed by the risks and harms; look no further than HPV vaccines, for example.”

Posted in medical practices, peer review, science is not truth | Tagged: , | 5 Comments »

Why skepticism about science and medicine?

Posted by Henry Bauer on 2020/09/06

My skepticism is not about science and medicine as sources or repositories of objective knowledge and understanding. Skepticism is demanded by the fact that what society learns about science and medicine is mediated by human beings. That brings in a host of reasons for skepticism: human fallibility, individual and institutional self-interest, conflicts of interest, sources of bias and prejudice.

I have never come across a better discussion of the realities about science and its role in society than Richard Lewontin’s words in his book, Biology as Ideology (Anansi Press 1991, HarperPerennial 1992; based on 1990 Massey Lectures, Canadian Broadcasting Corporation):

“Science is a social institution about which there is a great deal of misunderstanding, even among those who are part of it. . . [It is] completely integrated into and influenced by the structure of all our other social institutions. The problems that science deals with, the ideas that it uses in investigating those problems, even the so-called scientific results that come out of scientific investigation, are all deeply influenced by predispositions that derive from the society in which we live. Scientists do not begin life as scientists, after all, but as social beings immersed in a family, a state, a productive structure, and they view nature through a lens that has been molded by their social experience.
. . . science is molded by society because it is a human productive activity that takes time and money, and so is guided by and directed by those forces in the world that have control over money and time. Science uses commodities and is part of the process of commodity production. Science uses money. People earn their living by science, and as a consequence the dominant social and economic forces in society determine to a large extent what science does and how it. does it. More than that, those forces have the power to appropriate from science ideas that are particularly suited to the maintenance and continued prosperity of the social structures of which they are a part. So other social institutions have an input into science both in what is done and how it is thought about, and they take from science concepts and ideas that then support their institutions and make them seem legitimate and natural. . . .
Science serves two functions. First, it provides us with new ways of manipulating the material world . . . . [Second] is the function of explanation” (pp. 3-4). And (p. 5) explaining how the world works also serves as legitimation.

Needed skepticism takes into account that every statement disseminated about science or medicine serves in some way the purpose(s), the agenda(s), of the source or sources of that statement.

So the first thing to ask about any assertion about science or medicine is, why is this statement being made by this particular source?

Statements by pharmaceutical companies, most particularly their advertisements, should never be believed, because, as innumerable observers and investigators have documented, the profit motive has outweighed any concern for the harm that unsafe medications cause even as there is no evidence for definite potential benefit. The best way to decide on whether or not to prescribe or use a drug is by comparing NNT and NNH, the odds on getting benefit compared to the odds of being harmed; but NNT and NNH are never reported by drug companies. For example, there is no evidence whatsoever that HPV vaccination decreases the risk of any cancer; all that has been observed is that the vaccines may decrease genital warts. On the other hand, many individuals have suffered grievous harm from “side” effects of these vaccines (see Holland 2018 in the bibliography cited just below, and the documentary, Sacrificial Virgins. TV ads by Merck, for example in August 2020 on MSNBC, cite the Centers for Disease Control & Prevention as recommending the vaccine not only for girls but also for boys.

For fully documented discussions of the pervasive misdeeds of drug companies, consult the books listed in my periodically updated bibliography, What’s Wrong with Present-Day Medicine.
I recommend particularly Angell 2004, Goldacre 2013, Gøtzsche 2013, Healy 2012, Moynihan, & Cassels 2005. Greene 2007 is a very important but little-cited book describing how numbers and surrogate markers have come to dominate medical practice, to the great harm of patients.

Official reports may be less obviously deceitful than drug company advertisements, but they are no more trustworthy, as argued in detail and with examples in “Official reports are not scientific publications”, chapter 3 in my Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth (McFarland 2012):
“reports from official institutions and organizations . . . are productions by bureaucracies . . . . The actual authors of these reports are technical writers whose duties are just like those of press secretaries, advertising writers, and other public-relations personnel: to put on the actual evidence and conclusions the best possible spin to reinforce the bureaucracy’s viewpoint and emphasize the importance of the bureaucracy’s activities.
Most important: The Executive Summaries, Forewords, Prefaces, and the like may tell a very different story than does the actual evidence in the bulk of the reports. It seems that few if any pundits actually read the whole of such documents. The long public record offers sad evidence that most journalists certainly do not look beyond these summaries into the meat of the reports, given that the media disseminate uncritically so many of the self-serving alarums in those Executive Summaries” (p. 213).

So too with press releases from academic institutions.

As for statements direct from academic and professional experts, recall that, as Lewontin pointed out, “people earn their living by science”. Whenever someone regarded as an expert or authority makes public statements, an important purpose is to enhance the status, prestige, career, profitability, of who is making the statement. This is not to suggest that such statements are made with deliberate dishonesty; but the need to preserve status, as well as the usual illusion that what one believes is actually true, ensures that such statements will be dogmatically one-sided assertions, not judicious assessments of the objective state of knowledge.

Retired academic experts like myself no longer suffer conflicts of interest at a personal or institutional-loyalty level. When we venture critiques of drug companies, official institutions, colleges and universities, and even individual “experts” or former colleagues, we will be usually saying what we genuinely believe to be unvarnished truth. Nevertheless, despite the lack of major obvious conflicts of interest, one should have more grounds than that for believing what we have to say. We may still have an unacknowledged agenda, for instance a desire still to do something useful even as our careers are formally over. Beyond that, of course, like any other human beings, we may simply be wrong, no matter that we ourselves are quite sure that we are right. Freedom from frank, obvious conflicts of interest does not bring with it some superhuman capacity for objectivity let alone omniscience.

In short:
Believe any assertion about science or medicine, from any source, at your peril.
If the matter is of any importance to you, you had best do some investigating of evidence and facts, and comparison of diverse interpretations.

Posted in conflicts of interest, consensus, fraud in medicine, fraud in science, medical practices, peer review, politics and science, science is not truth, scientific literacy, scientism, scientists are human, unwarranted dogmatism in science | Tagged: , , , , | Leave a Comment »

Vaccines are not all equally safe and effective

Posted by Henry Bauer on 2019/07/13

The article below is copied from the website of the Roanoke Times:

https://www.roanoke.com/opinion/commentary/bauer-all-vaccines-are-not-equally-safe-and-effective/article_ef1bf6b6-4e8f-5dcd-b071-91736b99c68a.html

The article also appeared on the Opinion page of the Times on 11 July 2019.

The Roanoke Times is a local/regional newspaper in South-West Virginia. I had tried for a wider audience, but essentially the same piece had been rejected by the New York Times, Washington Post, Wall St Journal, and Financial Times.

Several people have been unable to access the Internet link given above, either asked to subscribe to the newspaper or told that it is not available outside the USA, but a number of people accessed it without difficulty.

Recent outbreaks of measles have brought widespread unrestrained criticism of parents who have avoided vaccinating their children under the presumed influence of misguided ideological “anti-vaxxers.” But at least some of the anger and blame should be directed at official sources for refusing to admit that some vaccines occasionally do bring sometimes very serious harm to some individuals. By not admitting that, officialdom provides unwarranted credibility to allegations of official cover- ups, allegations then expanded to blanket warnings against vaccinating in general.

There are three main ways in which vaccines can sometimes cause harm to some individuals.

One is the presence in some vaccines of preservatives to protect against contamination by bacteria. Being toxic to bacteria, they can also be toxic to higher forms of life. A commonly used preservative, thimerosal, is a mercury-containing organic substance, and organic-mercury compounds are indeed often toxic to human beings.

A second possible source of harm in some vaccines is the use of so-called adjuvants. These cause a non-specific stimulation of the immune system, in the belief that when the immune system is already aroused it will respond better to the specific components in the vaccine. Adjuvants work through being recognized by the immune system as foreign and undesirable, in other words as being potentially harmful to the person receiving the vaccine. Commonly used adjuvants include organic aluminum compounds, which are known to be harmful if they accumulate in the nervous system, particularly the brain; some people of my age may recall the long-ago warnings against aluminum cookware because of that possible harm.

A third possible danger lies in the inherent specific action of the particular vaccine. Some vaccines sometimes, though quite rarely, actually bring about the very disease against which they are intended to act. More generally, since vaccines are intended to cause the immune system to do certain things, it is far from implausible that the immune system may sometimes react in a different fashion than desired, for example by setting in process an autoimmune reaction. Our present understanding of immune-system functioning does not warrant dogmatic, supposedly authoritative pronouncements alleging that all vaccines are safe for everyone.

The known sources of possible harm from vaccination makes it not unreasonable, for instance, to recommend that babies be vaccinated against mumps, measles, and rubella separately, at intervals, rather than with a single dose of a multiple (MMR) vaccine. The known nervous-system toxicity of organic aluminum and mercury compounds makes it unreasonable to dismiss out-of-hand that these additives in some vaccines may produce such neural damage as symptoms of autism; reports and claims need to be investigated, not ignored or pooh-poohed. Moreover, wherever possible we should be offered the option of vaccines free of adjuvants and preservatives.

The public would be better served than we are now if official proclamations were to distinguish among different vaccines. The benefit-to-risk ratio of measles vaccine, for instance, or of polio vaccine, seems well established through long experience of efficacy and relative safety (“relative” because there is never 100.000…% certainty). By contrast, vaccines against HPV (human papillomavirus) have accumulated quite a substantial record of serious adverse events: the National Vaccine Injury Compensation Program of the Department of Health and Human Services had by 2013 awarded about $6 million to 49 victims in claims against HPV vaccines, with barely half of 200 claims adjudicated at that time; by May 2019, 130 of 480 claims against HPV vaccines had been compensated. Here the benefit-to-risk ratio is not known to be favorable because it cannot yet be known whether the vaccines actually prevent cervical or other cancers, it is only known that they act against viruses sometimes associated with cancer but never yet proven to actually cause cancer.

It is dangerous and without reasonable basis for ideological anti-vaxxers to raise alarm over all vaccinations because of instances like the HPV vaccines. But the conspiratorial and ideological anti-vaxxers are lent unwarranted public credibility and plausibility because officialdom refuses to admit the harm done by, for example, the HPV vaccines, while emphasizing the desirability of maintaining herd immunity against, say, measles, as though the same logic and practical experience applied to all vaccines including new, recently-devised ones. “Since they are lying to us about HPV vaccines, why should we trust them about measles vaccine?”
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
=============================================================

Dr. Christian Fiala, MD, adds:
You may add the experience that vaccines have been withdrawn because it became obvious that they were mainly dangerous and had little if any benefit, like Swine flu. Furthermore it because known in this case that most of the recommendations were by people paid for by the industry, including WHO ‚experts‘. This example is proof of the fact that pharmaceutical companies do in some cases exert a strong influence on bodies which are supposed to be neutral. Just like the Cochrane scandal.
The fact that these negative examples are totally left out by the vaccine lobby seriously harms their credibility.

Posted in conflicts of interest, consensus, media flaws, medical practices, peer review, prescription drugs, unwarranted dogmatism in science | Tagged: | 3 Comments »

Modern Psychiatric Diagnosis is Bullshit

Posted by Henry Bauer on 2019/07/09

I use the term   “bullshit”, of course, as the appropriate description of “assertions made without regard to whether or not they have any truth value”, following the analysis of professor of philosophy Harry Frankfurt in his book On Bullshit (Princeton University Press, 2005).

Those who commit bullshit orally or in writing do, of course, often imagine that they are asserting something that is true, but they are merely parroting popular shibboleths, “what everyone knows”,  without having taken any time it to examine the evidence for themselves (see Climate change is responsible for everything, as everyone knows (but what everyone knows is usually wrong).

Extraordinary as it may seem, the professional reference work on psychiatric diagnosis, the Diagnostic and Statistical Manual of Mental Disorders, published by the American Psychiatric Association and (since 2013) in its 5th edition (DSM-5), gives every appearance of having been put together without any careful attention to evidence, or for that matter to whether it makes any sense.

A couple of years ago, I pointed to the nonsense incorporated in DSM-5 about ADHD — Attention-Deficit/Hyperactivity Disorder (The banality of evil — Psychiatry and ADHD).

Now, the peer-reviewed professional journal Psychiatry Research has published a detailed analysis revealing that the diagnostic categories in DSM-5 make no sense in theory or in practice: (Allsopp et al., Heterogeneity in psychiatric diagnostic classification, Psychiatry Research 279 (2019) 15–22; https://doi.org/10.1016/j.psychres.2019.07.005).

It should suffice to offer two quotes:

“ [I]n the majority of diagnoses in both DSM-IV-TR and DSM-5 (64% and 58.3% respectively), two people could receive the same diagnosis without sharing any common symptoms.”

“[T]here are 270 million combinations of symptoms that would meet the criteria for both PTSD and major depressive disorder, and when five other commonly made diagnoses are seen alongside these two, the figure rises to one quintillion symptom combinations — more than the number of stars in the Milky Way.”

QED

Of course, the professional literature refrains from exposing its guild’s follies, the nakedness of the unclothed Emperor, to the general public, hence the article’s title is “Heterogeneity in psychiatric diagnostic classification”, unlikely to catch the eye of the uninitiated, rather than the plain “Modern psychiatric diagnosis is bullshit”, but both are saying the same thing. As George Bernard Shaw noted a century or so ago, “All professions are conspiracies against the laity”.

Posted in conflicts of interest, consensus, fraud in medicine, medical practices, peer review, science is not truth | Tagged: | Leave a Comment »

Science: Sins of Commission and of Omission

Posted by Henry Bauer on 2019/04/21

What statisticians call a type-I error is a scientific sin of commission, namely, believing something to be true that is actually wrong. A type-II error, dismissing as false something that happens to be true, could be described as a scientific sin of omission since it neglects to acknowledge a truth and thereby makes impossible policies and actions based on that truth.

The history of science is a long record of both types of errors that were progressively corrected, sooner or later; but, so far as we can know, of course, the latest correction may never be the last word, because of the interdependence of superficially different bits of science. If, for instance, general relativity were found to be flawed, or quantum mechanics, then huge swaths of physics, chemistry, and other sciences would undergo major or minor changes. And we cannot know whether general relativity or quantum mechanics are absolutely true, that they are not a type-I error — all we know is that they have worked usefully up to now. Type-II errors may always be hiding in the vast regions of research not being done, or unorthodox claims being ignored or dismissed.

During the era of modern science — that is, since about the 17th century — type-I errors included such highly consequential and far-reaching dogmas as believing that atoms are indivisible, that they are not composed of smaller units. A socially consequential type-I error in the first quarter of the 20th century was the belief that future generations would benefit if people with less desirable genetic characteristics were prevented from having children, whereby tens of thousands of Americans were forcibly sterilized as late as late as 1980.

A type-II error during the second half of the 19th century was the determined belief that claims of alleviating various ailments by electrical or magnetic treatments were nothing but pseudo-scientific scams; but that was corrected in the second half of the 20th century, when electromagnetic treatment became the standard procedure for curing certain congenital failures of bone growth and for treating certain other bone conditions as well.
Another 19th-century type-II error was the ignoring of Mendel’s laws of heredity, which were then re-discovered half a century later.
During the first half of the 20th century, a type-II error was the belief that continents could not have moved around on the globe, something also corrected in the latter part of the 20th century.

 

Science is held in high regard for its elucidation of a great deal about how the world works, and for many useful applications of that knowledge. But the benefits that society can gain from science are greatly restricted through widespread ignorance of and misunderstanding about the true history of science.

Regarding general social and political history, Santayana’s adage is quite well-known, that those who cannot remember the past are condemned to repeat it. That is equally true for the history of science. Since the conventional wisdom and the policy makers and so many of the pundits are ignorant of the fact that science routinely commits sins of both commission and omission, social and political policies continue to be made on the basis of so-called scientific consensus that may quite often be unsound.

In Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth (McFarland 2012), evidence is cited from well-qualified and respectable sources that the mainstream consensus is flawed on quite a number of topics. Some of these are of immediate concern only to scholars and researchers, for example about the earliest settlements of the Americas, or the extinction of the dinosaurs, or the mechanism of the sense of smell. Other topics, however, are of immediate public concern, for instance a possible biological basis for schizophrenia, or the cause of Alzheimer’s disease, or the possible dangers from mercury in tooth amalgams, or the efficacy of antidepressant drugs, or the hazards posed by second-hand tobacco smoke; and perhaps above all the unproven but dogmatic belief that human-generated carbon dioxide is the prime cause of global warming and climate change, and the long-held hegemonic belief that HIV causes AIDS.

The topic of cold nuclear fusion is an instance of a possible type-II error, a sin of omission, the mainstream refusal to acknowledge the strong evidence for potentially useful applications of nuclear-atomic transformations that can occur under quite ordinary conditions.

On these, and on quite a few other matters * as well, the progress of science and the well-being of people and of societies are greatly hindered by the widespread ignorance of the fact that science always has been and will continue to be fallible,   committing sins of both omission and of commission that become corrected only at some later time — if at all.

On matters that influence public policies directly, policy-makers would be greatly helped if they could draw on historically well-informed, technically insightful, and above all impartial assessments of the contemporary mainstream consensus. A possible approach to providing such assistance would be the establishing of a Science Court; see chapter 12 in Science Is Not What You Think: How It Has Changed, Why We Can’t Trust It, How It Can Be Fixed (McFarland 2017).

 

—————————————————-

*    Type-I errors are rife in the misapplications of statistics in medical matters, including the testing and approval of new drugs and vaccines; see the bibliography, What’s Wrong with Present-Day Medicine
      For a number of possible type-II errors, see for instance The Anomalist  and the publications of the Society for Scientific Exploration  and the Gesellschaft für Anomalistik

Posted in consensus, funding research, global warming, media flaws, medical practices, peer review, politics and science, resistance to discovery, science is not truth, science policy, scientific culture, scientific literacy, scientism, scientists are human, unwarranted dogmatism in science | Tagged: , , , | Leave a Comment »

Aluminum adjuvants, autoimmune diseases, and attempted suppression of the truth

Posted by Henry Bauer on 2019/03/24

An earlier post (Adjuvants — the poisons hidden in some vaccines) described the danger that aluminum adjuvants in vaccines pose, including that they may indeed be associated with a risk of inducing autism. A recent book, How to End the Autism Epidemic,   underscores that risk and exposes what should be the crippling, disqualifying conflicts of interest of one of the most prominent accepted experts on vaccinations. I had learned about this from a splendidly informative article by Celeste McGovern at Ghost Ship Media (Prescription to end the autism epidemic, 17 September 2018).

It turns out that animals as well as human beings have experienced tangible harm from vaccines containing aluminum adjuvants: in particular, sheep. Celeste McGovern has reported about that in other recent posts:
Spanish sheep study finds vaccine aluminum in lymph nodes more than a year after injection, behavioural changes, 3 November 2018; Vaccines induce bizarre anti-social behaviour in sheep, 6 November 2018; Anatomy of a science study censorship, 20 March 2019.

This last piece describes the attempt to prevent the truth about aluminum adjuvants from becoming public knowledge, by pressuring the publisher, Elsevier, to withdraw an already accepted, peer-reviewed article in one of its journals: “Cognition and behavior in sheep repetitively inoculated with aluminum adjuvant-containing vaccines or aluminum adjuvant only”, by Javier Asína et al., published online in Pharmacological Research before being withdrawn. Fortunately there are   nowadays resources on the Internet that make it more difficult for the censors to do their dirty work. One invaluable resource is the Wayback Machine, which too few people seem to know about. In the present case, a PDF of the Asína et al. article, as accepted and published online as “In Press” in Pharmacological Research, is available at ResearchGate.

Elsevier publishes thousands of scientific and medical journals, including in the past some that were actually advertisements written by and paid for by pharmaceutical companies, presented dishonestly and misleadingly as genuine scientific periodicals: Elsevier published 6 fake journals); Elsevier had a whole division publishing fake medical journals).

Elsevier had also engaged in censorship on earlier occasions, in one case to the extent of emasculating a well respected, independent publication, Medical Hypotheses (see Chapter 3, “A Public Act of Censorship: Elsevier and Medical Hypotheses”, in Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth).

If the shenanigans and cover-ups about aluminum adjuvants make an insufficiently alarming horror story,   please look at yet another article by Celeste McGovern: Poisoned in Slow Motion, 1 October 2018:

“Immune-system disease is sweeping the globe. . . . Autoimmune/inflammatory syndrome induced by adjuvants, or ASIA — a wildly unpredictable inflammatory response to foreign substances injected or inserted into the human body . . . . The medical literature contains hundreds of such cases. . . . [with] vague and sundry symptoms — chronic fatigue, muscle and joint pain, sleep disturbances, cognitive impairment, skin rashes and more . . . that . . . share the common underlying trigger of certain immune signaling pathways. Sometimes this low-grade inflammation can smolder for years only to suddenly incite an overt autoimmune disease. . . . Chronic fatigue syndrome (also known as myalgic encephalitis), once a rare “hypochondriac” disorder, now affects millions of people globally and has been strongly associated with markers of immune system dysfunction. . . . One in thirteen American children has a hyperactive immune system resulting in food allergy,4 and asthma, another chronic inflammatory disease of the immune system, affects 300 million people across the globe.5 Severe neurological disorders like autism (which now affects one in 22 boys in some US states) have soared from virtual nonexistence and are also linked to a damaged immune system.”

[4. Pediatrics, 2011; 128: e9-17
5. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. 2008.
6. Eur J Pediatr, 2014; 173: 33-43]

******************************************************************

These particulars offer further illustrations of the general points that I have been making for some time:

 Science and medicine have become dogmatic wielders of authority through being co-opted and in effect bought out by commercial interests. Pharmaceutical companies are perhaps in the forefront of this takeover, but the influence of other industries should not be forgotten, for instance that of Monsanto with its interest in Genetically Modified products; see Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth, Jefferson (NC): McFarland 2012

 Science, research, medicine, are very different things nowadays than they were up to about the middle of the 20th century, and very different from the conventional wisdom about them. Media, policy makers, and the public need an independent, impartial assessment of what science and medicine are said to have established; needed is  a Science Court; see Science Is Not What You Think: How It Has Changed, Why We Can’t Trust It, How It Can Be Fixed, McFarland, 2017

Posted in conflicts of interest, fraud in medicine, fraud in science, legal considerations, media flaws, medical practices, peer review, prescription drugs, science is not truth, scientific culture, scientific literacy, scientism, scientists are human, unwarranted dogmatism in science | Tagged: , , , , , , | Leave a Comment »

Optimal peer review for guiding public policy: A Science Court

Posted by Henry Bauer on 2019/01/29

“Peer review” is widely regarded as the mechanism by which science manages to produce impartial, unbiased, objective facts and interpretations. As with so many popular notions about scientific activity, this is very far from the truth [1].

Innumerable observers and practicing researchers have written copiously about the many things that are wrong with peer review [2]. Contemporary practices of peer review are only about a century old. They began simply as a way of assisting editors of journals to assess the merits for publication of manuscripts too specialized for the editorial staff itself it to render judgment. The need for such specialized advice was not unrelated to the enormous expansion of scientific activity that followed World War II, bringing an ever-increasing demand for space in scientific periodicals as well as ever-increasing competition between researchers for funding and for getting published as a necessary prerequisite for career advancement and resources for research.

At any rate, peer review in science is no more impartial, unbiased, or objective than is criticism of art, music, film, or literary products. One illustration of that: it is becoming quite common for journal editors to ask the authors of submitted manuscripts whether there are individuals who should not be asked to serve as peer reviewers because of their known biases or hostility against the authors. Another point: Peer reviewers are typically chosen because they work on much the same topic as that of the manuscript to be reviewed; thereby they are likely to be to some extent competitors or allies, conflicts of interest that ought to be disbarring.

Modern (post-16th-17th-century) science managed to progress and to succeed quite magnificently for several centuries without the current practices of systematic peer-review. The assessing of already published work through further research and commentary gave science the appearance and the effect of being eventually self-correcting. Note “eventually”: the trials and errors and that preceded correction, sometimes for very long periods indeed, were of concern only within the specialized scientific communities, they were not any problem for the wider society.

Nowadays, however, society in general and industries and governments in particular have come to look to contemporary science for immediate guidance to significant actions and policies. That makes the fact that peer review is not impartial or objective quite important, and indeed dangerous. The nature of scientific activity and of the scientific community is such that the consensus among those who happen to be the most prominent researchers in any given field comes to control what research gets funded, which results get published and which are suppressed, and what the media and the public and policy-makers take to be “what science says”.

Unfortunately, the history of science is far from widely known or appreciated, most notably the fact that the contemporary scientific consensus at any given time has almost invariably turned out, sooner or later, to have been flawed, in minor or major ways.

Ignorance of the history of science, together with the misguided view that any prominent contemporary scientific consensus can be safely relied upon to guide social and political actions on any matters that are technical, including matters of medicine and public health, have already resulted in widespread actions that have brought tangible harm on such issues as supposedly human-caused global warming and climate change [3] and the mistaken belief is that AIDS was caused by a novel virus that destroys the immune system [4]. The closest precedent for these contemporary mistakes seems to be the ideology of eugenics, which led to the forced sterilization of tens of thousands of Americans over a period of more than half a century.

Since peer-review is not effectively making science contemporaneously objective and reliable, on matters of social and political importance policymakers badly need some other way to counteract the bias and dogmatic single-mindedness of any contemporary scientific consensus. The only conceivable mechanism to that end would seem to be something like an Institution of Scientific Judgment, as Arthur Kantrowitz suggested half a century ago [5], a concept that has come to be described as a Science Court [6].

 

———————————————-

[1]  Science Is Not What You Think — how it has changed, why we can’t trust it, how it can be fixed (McFarland, 2017)

[2]  pp. 106-9 in [1] and sources cited there

[3]  “What everyone ought to know about global warming and climate change: an unbiased review”referring to “#16 A Summary” by Don Aitkin

[4]  The Case against HIV  and sources cited there

[5]  Arthur Kantrowitz, “Proposal for an Institution for Scientific Judgment”, Science, 156 (1967) 763–4.

[6]  Chapter 12 in [1] and sources cited there

Posted in conflicts of interest, consensus, funding research, global warming, media flaws, peer review, politics and science, science is not truth, science policy, scientific culture, scientists are human, unwarranted dogmatism in science | Tagged: , | Leave a Comment »

What everyone ought to know about global warming and climate change: an unbiased review

Posted by Henry Bauer on 2018/09/11

“What everyone knows” is that burning fossil fuels releases carbon dioxide, a “greenhouse gas” that holds in heat, warming the Earth and causing climate change, with catastrophic consequences if it isn’t stopped soon.

All official agencies, all mainstream scientific groups, say that.

What few people know is that a considerable number of experts and informed observers do not believe this AGW scenario to be correct: AGW = Anthropogenic Global Warming, global warming caused by human actions.

Those dissenting experts point out that actual data on temperature and carbon-dioxide levels, over the life of the Earth but also over the last century, show that carbon dioxide does not cause high global temperature.

But few people, again, can believe that “everyone” could be wrong about this, that “science” could be so dogmatically wrong. To form an opinion as to the relative merits of the official view and of the dissenting experts, therefore requires not only looking at the data but also at how the official view came into bring and how and why it persists. Few people want to take the time and make the effort to wade through huge amounts of writings by opposing advocates to ferret out the genuine facts and legitimate conclusions, which often calls for reading between the lines and being skeptical about everything.

My recent discovery of the Peter Ridd affair had a wonderfully beneficial consequence, learning about the writings of Don Aitkin, an Australian whose academic career included research on social and political matters as well as administrative experience that included heading a university (as Vice-Chancellor and President of the University of Canberra). Aitkin spent a decade or more reading and thinking about AGW, and summarized what he learned in a series of blogs. The last in the series, #16,  sums things up and has appropriate links to the earlier ones which concentrate on different aspects of the matter.

This offers a wonderfully convenient way for anyone to become genuinely informed about AGW, and “climate-change denialism”, and incidentally about the interaction between science and public policy. Aitkin is factually reliable and ideologically unbiased, an all-too-rare combination.

*                     *                   *                   *                   *                   *                   *                   *

My appreciation of Aitkin’s series on global warming was enhanced when he noted that the hysteria over AGW “bridges the space between science and politics in an almost unprecedented way, though it has some similarities to the ‘eugenics’ issue a hundred years ago”, something that had occurred to me also.

Another Aitkin blog-post, “A good starting position in discussions about ‘climate change’” cites the salient points made by Ben Pile at Climate Resistance:

  1. There is good scientific evidence that human activities are influencing the climate. But evidence is not fact, and neither evidence nor fact speak for themselves.
  2. The evidence for anthropogenic climate change is neither as strong nor as demanding of action as is widely claimed.
  3. Our ability to mitigate, let alone to reverse, any such change through reductions in CO2 emissions is even less certain, and may itself be harmful.
  4. The scientific consensus on climate change as widely reported inaccurately reflects the true state of scientific knowledge.
  5. How society should proceed in the face of a changing climate is the business of politics not science.
  6. Political arguments about climate change are routinely mistaken for scientific ones. Environmentalism uses science as a fig-leaf to hide an embarrassment of blind faith and bad politics.
  7. Science is increasingly expected to provide moral certainty in morally uncertain times.
  8. The IPCC is principally a political organisation.
  9. The current emphasis on mitigation strategies is impeding society’s ability to adapt to a changing climate, whatever its cause.
  10. The public remains unconvinced that mitigation is in its best interest. Few people have really bought into Environmentalism, but few people object vehemently to it. Most people are slightly irritated by it.
  11. And yet climate change policies go unchallenged by opposition parties.
  12. Environmentalism is a political ideology, yet it has never been tested democratically.
  13. Widespread disengagement from politics means that politicians have had to seek new ways to connect with the public. Exaggerated environmental concern is merely serving to provide direction for directionless politics.
  14. Environmentalism is not the reincarnation of socialism, communism or Marxism. It is being embraced by the old Right and Left alike. Similarly, climate change scepticism is not the exclusive domain of the conservative Right.
  15. Environmentalism will be worse for the poor than climate change.
  16. Environmentalism is a self-fulfilling prophecy.

*                   *                  *                     *                   *                   *                   *                   *

Aitkin is an Australian, and any connection to Australia always rekindles my appreciation for the sanctuary Australia provided the refuigee Bauers and the excellent public education from which I benefited in elementary school (Picton, NSW), at The Sydney Boys’ High School, and at the University of Sydney (moreover, in those years, at almost no cost to my parents!).
Browsing Aitkin’s writings, I came across an after-dinner speech about “Australian values”  that rings true to my own recollections and also, I think, offers some insights into the similarities and differences between American and Australian life.

Posted in conflicts of interest, consensus, denialism, funding research, global warming, media flaws, peer review, politics and science, resistance to discovery, science is not truth, science policy, scientific culture, scientific literacy, scientism, scientists are human, unwarranted dogmatism in science | Tagged: , , | 3 Comments »

What everyone knows is all too often wrong: dinosaur extinction, and much more

Posted by Henry Bauer on 2018/08/26

“What everyone knows” is all too often wrong, as I pointed out years ago, specifically about science punditry and TED talks and books;  and about climate change;  see also Who guards the guardians? Who guards science?; “Dangerous knowledge”; Dangerous knowledge II: Wrong knowledge about the history of science;  Dangerous knowledge III: Wrong knowledge about scienceDangerous knowledge IV: The vicious cycle of wrong knowledge.

Perhaps the main reason for “everyone” being wrong about so many things is that most of us take our knowledge on most or even all matters on the authority of other people, and those are all too often unwitting or witting false prophets [1]. Very few people ever bother to look for themselves into what the actual evidence is for commonly held beliefs.

I had become interested long ago in what science is and how it works, and my academic work came to focus on the “hard cases”: controversies in science, particularly the roles played by minority views and claims. So I had the time as well as the interest to dig quite deeply into the facts underlying a number of controversies, including controversies that the mainstream asserts not to be controversial. That is how I came to realize, for example, that HIV has never been proven to be the cause of AIDS, indeed has never even been proven to exist [2].

When I have the occasion to encounter someone who parrots HIV=AIDS theory, which “everyone knows”, I like to ask, “How do you know that HIV causes AIDS?”

Almost invariably the answer is, “Everyone knows that”.

Exactly. QED.

Increasingly since the 19th century, perhaps since about the early-to-middle 19th century, “science” has become the authority for most people as well as for organizations both private and public [3]. That even includes many scholars and pundits of whom one might expect better: When I had first collated HIV-test data and was giving talks about the failings of HIV/AIDS theory, a sociologist in a Science-Studies program said that I must be wrong because “tens of thousands of papers” had been published in the HIV=AIDS genre.

Until the most recent few decades, science has rarely played the role of false prophet on issues sufficiently salient as to inform public policies and actions; an exception in the first quarter of the 20th century was when misguided expert opinion about genetics and heredity led to the forced sterilization of tens of thousands of Americans [4].

Nowadays, unfortunately, science has grown so large and unwieldy as to be in many ways dysfunctional [5], so that it has given bad advice on at least two matters of considerable public importance: not only HIV/AIDS [2] but also climate change [6].

In past times and on less prominent issues whose significance rarely matters outside the scientific community itself, “science” has quite typically been wrong before it got things right. The “scientific consensus” at any given time is tentative and temporary; yet, human nature being what it is, the elite proponents of the consensus have always defended their view vigorously, including denigrating and even persecuting fellow scientists who disagree [7].

A case in point is the view that the extinction of the dinosaurs about 65 million years ago was caused by the impact on Earth of a large asteroid. A splendid recent article in the Atlantic magazine [9] gives full details of the career gauntlets run by paleontologist Gerta Keller as she has been amassing evidence against the asteroid hypothesis and for the earlier theory that the extinction was brought on by a lengthy episode of recurring intense volcanism — for perhaps 350,000 years, with particularly intense eruptions during the 100,000 or so years that coincide with the extinction. (Calculating the timing of happenings 65 million years ago is unlikely ever to permit accuracy of better than some tens of thousands of years.)

A point that seems powerful to a lay person like myself is that the dinosaur extinction was the fifth major mass extinction indicated by the fossil record, and expert opinion seems to be almost undivided that the first four extinctions had been caused by extremes of volcanic action.

The Atlantic article is also commendably accurate about contemporary science in noting how vigorously the mainstream consensus, the ruling elite, defends its point of view, how unscrupulously at least some members of that elite and their acolytes attack those who dissent; science has become riddled with knowledge monopolies.

Many examples of that sad state of affairs are at hand in a number of other fields [7]: Big-Bang cosmology, amyloid plaque as cause of Alzheimer’s disease, anti-depressant and other prescription drugs, first human settlement of the Americas, nuclear “cold fusion”, dangers of second-hand smoke, plate tectonics (“continental drift”), mechanism of the sense of smell, physiological correlates of schizophrenia, risks from mercury compounds in tooth fillings and in vaccines, possible relation between certain multiple vaccines and autism… .

It is really quite stunning, how many cases there are where “what everyone knows”, namely, the reigning scientific consensus, is questionable in light of the actual evidence, the unquestioned data.

 

That last is a most important thing that everyone does not know but should.

 

————————————————————————

[1]    As an academic Dean once remarked “Saying so, makes it so”, when the sayer is someone in some sort of authority.

[2]    Henry H. Bauer, The Origin, Persistence and Failings of HIV/AIDS Theory, McFarland 2007; “The Case against HIV”

[3]    David Knight, The Age of Science, Basil Blackwell, 1986

[4]    “Bauer: Could science mislead public policy?”, Roanoke Times, 10 June 2018;

[5]    Henry H. Bauer, Science Is Not What You Think — how it has changed, why we can’t trust it, how it can be fixed (McFarland, 2017)

[6]    For many discussions, with source references, about the politicized nature of this controversy and the fact that the actual observational data do not support the hypothesis of carbon-dioxide-induced global warming (let alone carbon-dioxide-induced climate change), see the articles at https://scimedskeptic.wordpress.com/ that come up when setting “climate change” in the “Search” box.

[7]    The literature on these points is vast. Pertinent sections of reference [5] cover much of this ground and cite many other sources; see also reference [8].

[8]    Henry H. Bauer, Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth, McFarland 2012

[9]    Bianca Bosker, “The nastiest feud in science”, Atlantic, September 2018

Posted in consensus, denialism, media flaws, peer review, politics and science, resistance to discovery, science is not truth, science policy, scientific culture, scientific literacy, scientism, scientists are human, unwarranted dogmatism in science | Tagged: , , , | 2 Comments »

Intellectual charlatanry: TED doesn’t know how to distinguish between good science and bad science

Posted by Henry Bauer on 2018/08/07

On the Mad in America website I came across “TED betrays its own brand by flagging nutrition talk”. After following a number of links, I was led to the guidelines that the TED organization prescribes for talks eligible to be described as “TEDx” (“TEDx is an international community that organizes TED-style events anywhere and everywhere — celebrating locally-driven ideas and elevating them to a global stage. TEDx events are produced independently of TED conferences, each event curates speakers on their own, but based on TED’s format and rules.”).

Sadly, TED’s guidelines for what constitutes good science reveal abysmal ignorance:

Claims made using scientific language should:

  • Be testable experimentally.
    That would exclude all the science that relies only on observation because experimenting is not possible: astronomy, cosmology, geology, parts of biology, almost everything to do with human beings…. String theory, which presently dominates theoretical physics, is not testable experimentally, nor is cosmology’s consensus that “the universe” originated in a Big Bang about 13 billion years ago. And so on, The theory of evolution by natural selection is not testable experimentally.
    Much of what is nowadays regarded as “accepted science” or “settled science   consists just of reasonably solid observations supporting more or less plausible inductive explanations.
  • Have been published in a peer-reviewed journal (beware… there are some dodgy journals out there that seem credible, but aren’t. For further reading, here’s an article on the topic).
    The cited article does not begin to cover this issue. Peer review is not the guarantor of reliability that it is so widely taken to be (pp. 106-9 in “Science Is Not What You Think — how it has changed, why we can’t trust it, how it can be fixed”).
    Even what is published in highly regarded, long-established, peer-reviewed journals may be quite wrong. Perhaps 90% of the primary research literature in physics later turns out to have been faulty or flawed in some way (John Ziman, “Reliable Knowledge”, Cambridge University Press, 1978, p. 40). As an editor of The Lancet (Richard Horton) once put it, “Peer review … is simply a way to collect opinions from experts in the field. Peer review tells us about the acceptability, not the credibility, of a new finding”
    .
    What peer review does very effectively is to entrench whatever the prevailing majority consensus happens to be; but the history of science is perfectly clear that any majority consensus may have a very limited useful life before it is superseded.
  • Be based on theories that are also considered credible by experts in the field.
    Thereby entrenching the possibly wrong contemporary consensus.
  • Be backed up by experiments that have generated enough data to convince other experts of its legitimacy.
    Nonsense, see detailed comments above.
  • Have proponents who are secure enough to acknowledge areas of doubt and need for further investigation.
    Proponents of a contemporary consensus are rarely so “scientific”.
  • Not fly in the face of the broad existing body of scientific knowledge.
    Again, thereby entrenching the possibly wrong contemporary consensus.
  • Be presented by a speaker who works for a university and/or has a phD [sic] or other bona fide high level scientific qualification.
    When we founded the Society for Scientific Exploration (which Wikipedia and other science-ignorant sources describe as a “fringe science” organization) it was made a requirement for full membership that applicants have a PhD or equivalent credentials. I found that rather funny, since anyone even slightly acquainted with academe or people with PhDs knows that these are absolutely no warranty of intelligence or competence or lack of kookiness.
  • Show clear respect for the scientific method and scientific thinking generally.
    “The scientific method” is a myth (“Scientific Literacy and Myth of the Scientific Method”, University of Illinois Press, 1992), and “scientific thinking” is no more easily defined than “the method” 

    Claims made using scientific language should not:

  • Be so obscure or mysterious as to be untestable
    See above re testable
  • Be considered ridiculous by credible scientists in the field
    Once more, relies on current consensus
  • Be based on experiments that can not be reproduced by others.
    For misguided views that “reproducibility” is a necessary criterion and is applied in practice, see pp. 53ff. in “Science Is Not What You Think”, book cited above
  • Be based on data that do not convincingly corroborate the experimenter’s theoretical claims.
    “Convincing” is in the eyes of the beholder
  • Come from overconfident fringe experts.
    Mainstream experts often suffer from overconfidence, and labeling someone a “fringe expert” is no easy matter
  • Use over-simplified interpretations of legitimate studies
    Simplification is a necessity in teaching and in talking to general audiences; what is “over” simplified is again in the eyes of the beholder

—————————————————————-

My detailed comments should make plain that whoever drew up these guidelines was insufficiently knowledgeable about science. That’s rather serious for an organization that says:
“Science is a big part of the TED universe, and it’s important that TEDx organizers sustain our reputation as a credible forum for sharing ideas that matter. It’s not always easy to distinguish between real science and pseudoscience…”

Indeed it isn’t, see for example Science or Pseudoscience: Magnetic Healing, Psychic Phenomena, and Other Heterodoxies (University of Illinois Press, 2001). It is likely to be impossible for an organization whose guidelines for distinguishing are ignorant rubbish, as above. And so it happened that TED “flagged” a TEDx talk about micronutrients and mental health given by a well-published PhD professor at a very respectable university:

“NOTE FROM TED: We’ve flagged this talk, which was filmed at a TEDx event, because it appears to fall outside TEDx’s curatorial guidelines. There is limited evidence to support the claims made by this speaker. Please do not look to this talk for medical advice.”

For comments on this flagging, see James Moore’s blog post “Julia Rucklidge: Nutrition, Mental Health and TED” which includes an audio of Moore’s interview with Rucklidge in which she describes the flagging (starting at about 18 minutes in the 30-minute interview).

My point here is not, however, just that the flagging was unwarranted. Anyone can learn that easily enough by checking Rucklidge’s publications and following a few other links. My point is to expose TED as practicing charlatanry, falsely claiming expertise it does not possess (“charlatan: a person falsely claiming to have a special knowledge or skill; a fraud, quack, sham, fake, impostor, hoaxer, cheat, deceiver, double-dealer, swindler, fraudster, mountebank; (informal) phony, shark, con man, con artist, scam artist, flimflammer, bunco artist, shyster, snake oil salesman; (dated) confidence man/woman”).

Not only charlatanry: sheer incompetence, and arrogant incompetence at that. Rucklidge’s TEDx talk was flagged by TED without notifying Rucklidge or the organizers of her talk. When Rucklidge learned of this, she wanted to find out the reason for the flagging — but has been unable to get any pertinent information from TED! However, TED did eventually modify the text of its flag, to:

“NOTE FROM TED: We’ve flagged this talk, which was filmed at a TEDx event, because it appears to fall outside TEDx’s curatorial guidelines. Given that the intersection of nutrition and mental health is an emerging field of study with limited conclusive evidence, please consult with a mental health professional and do not look to this talk for medical advice.” (https://www.youtube.com/watch?v=3dqXHHCc5lA)

This still impugns Rucklidge’s reputation as a legitimate, credible scientist by claiming it is “outside TEDx’s curatorial guidelines”. That is an outrage; and no less an outrage that TED flags a talk without consulting its author and its sponsor, something that decency as well as plain common sense would dictate.

The only obvious reason for anyone to object to Rucklidge’s talk and work is that she points out that presently used psychiatric drugs do not work for some significant proportion of people who need help; and so mainstream psychiatry and Big Pharma may well feel challenged. But this remains conjecture so long as TED will not explain its actions. Clearly, TED ought to be held accountable; but how?

That question is likely to become more frequent and more pressing as time goes by, because it pertains not only to TED but to an increasing number of ventures on the Internet — Facebook, Twitter, etc., the whole genre nowadays categorized as “social media”.

Perhaps a first necessary step is for the realization to become general and widespread, that “social media” includes TED, TEDx, Wikipedia, and innumerable other sites that offer all sorts of purportedly authoritative, reliable information — dictionary definitions, say — and yet have no evident credentials and are frequently anonymous, offering no contactable individual who could be held accountable for errors or for committing personal libel like that visited on Professor Rucklidge.

In her interview with Moore, Rucklidge mentions the classic case of Semmelweiss as an example of unconventional work that was wrongly disdained by contemporary mainstream experts. Unfortunately, this and the fact of many similar cases are known usually only to historians of science or medicine; for further examples see Dogmatism in Science and Medicine: How Dominant Theories Monopolize Research and Stifle the Search for Truth).

See also my long-ago post, “TED and TEDx reinvent the wheel — and get it all wrong (or, Ignorant punditry about science and pseudo-science)”

Posted in consensus, media flaws, peer review, resistance to discovery, the scientific method, unwarranted dogmatism in science | Tagged: , , , , | Leave a Comment »

 
%d bloggers like this: